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Gary Null Show Notes

Effects of strawberries on bone biomarkers in pre- and stage 1-hypertensive postmenopausal women

Florida State University Postmenopausal women experience an increase in bone remodeling with the rate of bone resorption superseding the rate of bone formation. This results in a net bone loss with a subsequent increased risk for osteoporosis and fractures. Strawberries are rich in polyphenols, which have been shown to have anti-hypertensive and bone-protective properties. Thus, we examined whether daily intake of strawberries would positively affect biomarkers of bone metabolism in postmenopausal women with pre- and stage 1-hypertension. After eight weeks, osteocalcin increased in the 50 g FDSP group with a large effect size (d = 0.6) when compared to the placebo-control group. Adiponectin increased by 5% and 6% in the 25 g and 50 g FDSP groups, respectively, while it declined in the placebo-control group by 25% (P = 0.03 for time-by-treatment interaction). Our findings suggest that consumption of 25 g FDSP increases IGF-1 in postmenopausal women with pre- and stage 1-hypertension.
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Dietary supplement use by individuals living with and beyond cancer

University College London, December 20, 2021 New research indicates that many individuals living with and beyond cancer use dietary supplements, often with the belief that the products will reduce the risk of cancer recurrence. Published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings reveal a need for health care professionals to provide advice and clarity to patients about the appropriate use of dietary supplements. To explore factors associated with dietary supplement use in cancer survivors, Rana Conway, PhD, RNutr, of University College London (UCL), and her colleagues studied 1,049 adults who had been diagnosed with breast, prostate, or colorectal cancer in the United Kingdom.

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Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial

Nutrition Research Centre Ireland, December 20, 2021 Accumulating evidence suggests that omega-3 fatty acids (ω-3FAs), carotenoids and vitamin E can improve cognitive performance. However, their collective impact on cognition has not yet been investigated in healthy individuals. This study investigated the combined effect of ω-3FA, carotenoid and vitamin E supplementation on the cognitive performance of older adults.

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A high-fiber diet may improve the response of melanoma patients to immunotherapy

University of Texas and National Cancer Institute, December 23, 2021 A diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment by influencing the gut microbiome, according to a new study led by researchers at the Center for Cancer Research at the National Cancer Institute (NCI), part of the National Institutes of Health, and the University of Texas MD Anderson Cancer Center.

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Could meditation strengthen your immune system?

University of Florida’s College of Medicine, December 23, 2021 Meditation done at an intense level may bring a significant boost to the inner workings of your immune system. That analysis suggested that meditation boosted the activity of hundreds of genes known to be directly involved in regulating immune response. But the researchers stressed that their study involved 10-hour daily marathon meditation sessions conducted for eight straight days in total silence. In the real world, most people would be hard-pressed to replicate those methods. The eight-day retreat provided all participants with vegan cuisine, and all followed a regular sleep schedule. Meditation sessions lasted 10 hours a day and were conducted in silence.

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Even light-intensity exercise might reduce dementia risk

Yonsei University College of Medicine (South Korea), December 22, 2021 In a new study, researchers have identified an association between light-intensity physical exercise in older adults and a reduced risk of dementia. In the present study, researchers investigated whether there was an association between doing light-intensity physical exercise and a reduced risk of developing dementia in older adults. The study involved 62,286 participants who were 65 years or older, did not have a dementia diagnosis, and had medical records in the Korean National Health Insurance Service database. Researchers gathered data between January 2009 and December 2012 and tracked the participants until the end of December 2013. They completed data analysis from July 2020 to January 2021.

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Fast-food consumption linked to lower test score gains in 8th graders

The more children ate in 5th grade, the slower their academic growth by 8th grade Ohio State University, December 22, 2021 The amount of fast food children eat may be linked to how well they do in school, a new nationwide study suggests. Researchers found that the more frequently children reported eating fast food in fifth grade, the lower their growth in reading, math, and science test scores by the time they reached eighth grade. Students who ate the most fast food had test score gains that were up to about 20 percent lower than those who didn’t eat any fast food, said Kelly Purtell, lead author of the study and assistant professor of human sciences at The Ohio State University.

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Open letter from The BMJ to Mark Zuckerberg

Dear Mark Zuckerberg, We are Fiona Godlee and Kamran Abbasi, editors of The BMJ, one of the world’s oldest and most influential general medical journals. We are writing to raise serious concerns about the “fact checking” being undertaken by third party providers on behalf of Facebook/Meta. In September, a former employee of Ventavia, a contract research company helping carry out the main Pfizer covid-19 vaccine trial, began providing The BMJ with dozens of internal company documents, photos, audio recordings, and emails. These materials revealed a host of poor clinical trial research practices occurring at Ventavia that could impact data integrity and patient safety. We also discovered that, despite receiving a direct complaint about these problems over a year ago, the FDA did not inspect Ventavia’s trial sites. The BMJ commissioned an investigative reporter to write up the story for our journal. The article was published on 2 November, following legal review, external peer review and subject to The BMJ’s usual high level editorial oversight and review.[1] But from November 10, readers began reporting a variety of problems when trying to share our article. Some reported being unable to share it. Many others reported having their posts flagged with a warning about “Missing context … Independent fact-checkers say this information could mislead people.” Those trying to post the article were informed by Facebook that people who repeatedly share “false information” might have their posts moved lower in Facebook’s News Feed. Group administrators where the article was shared received messages from Facebook informing them that such posts were “partly false.” Readers were directed to a “fact check” performed by a Facebook contractor named Lead Stories.[2] We find the “fact check” performed by Lead Stories to be inaccurate, incompetent and irresponsible. — It fails to provide any assertions of fact that The BMJ article got wrong — It has a nonsensical title: “Fact Check: The British Medical Journal Did NOT Reveal Disqualifying And Ignored Reports Of Flaws In Pfizer COVID-19 Vaccine Trials” — The first paragraph inaccurately labels The BMJ a “news blog” — It contains a screenshot of our article with a stamp over it stating “Flaws Reviewed,” despite the Lead Stories article not identifying anything false or untrue in The BMJ article — It published the story on its website under a URL that contains the phrase “hoax-alert” We have contacted Lead Stories, but they refuse to change anything about their article or actions that have led to Facebook flagging our article. We have also contacted Facebook directly, requesting immediate removal of the “fact checking” label and any link to the Lead Stories article, thereby allowing our readers to freely share the article on your platform. There is also a wider concern that we wish to raise. We are aware that The BMJ is not the only high quality information provider to have been affected by the incompetence of Meta’s fact checking regime. To give one other example, we would highlight the treatment by Instagram (also owned by Meta) of Cochrane, the international provider of high quality systematic reviews of the medical evidence.[3] Rather than investing a proportion of Meta’s substantial profits to help ensure the accuracy of medical information shared through social media, you have apparently delegated responsibility to people incompetent in carrying out this crucial task. Fact checking has been a staple of good journalism for decades. What has happened in this instance should be of concern to anyone who values and relies on sources such as The BMJ. We hope you will act swiftly: specifically to correct the error relating to The BMJ’s article and to review the processes that led to the error; and generally to reconsider your investment in and approach to fact checking overall. Best wishes, Fiona Godlee, editor in chief Kamran Abbasi, incoming editor in chief The BMJ Competing interests: As current and incoming editors in chief, we are responsible for everything The BMJ contains.