One of the criteria the Food and Drug Administration considers when deciding whether or not to approve a GMO is called “substantial equivalence.” This means the nutritional profile and toxicity levels of the modified plant are within the same range as a non-modified plant. When a new strain of corn is similar enough to the original to demonstrate substantial equivalence, the product is free to pass to market with fewer safety checks. A new study looking more closely at the differences between a specific variety of GM corn, Monsanto’s NK603, and the non-modified corn it is derived from is challenging that principle.