The Centers for Disease Control (CDC) report minor side effects from the MMR-V and MMR vaccines to include low-grade fever, injection site redness or rash, pain at the injection site, and facial swelling. Moderate side effects include a full body rash, temporary low platelet count, temporary stiffness and pain at the joints, and seizures.1 2
There is a significantly greater risk of seizures following MMR-V vaccine in comparison to separate administrations of MMR and varicella vaccines if the MMR-V is given as the first dose of the series.3