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- (‘VAX’) The CDC Knew Before The Rollout That It Is Going To Be A Disaster Of Side Effects (8:00)
- Senator Malcolm Roberts 🚨 WARNING 🚨 : World Health Organisation’s Dictator style power grab (2:40)
- This WEF plan is the most INSANE one yet | Redacted with Natali and Clayton Morris (10:00)
- The Re-Education of Jordan Peterson: Why His Clinical Psychology License is Under Threat (9:00)
Twelve Intervention Trials Conclude That Vitamin C Works for Covid
Orthomolecular News Service, January 31, 2023
A review of twelve studies, including five “gold standard” randomized controlled trials, shows that this simple vitamin saves lives when given in the right dose. Vitamin C can prevent a serious Covid infection.
The scientific evidence is clear: vitamin C taken when infected can reduce Covid symptoms and duration of illness. So why aren’t we being told to supplement with vitamin C?
The review of the twelve studies, which includes five randomized controlled trials, is published in the journal Life. The review was carried out and funded by VitaminC4Covid, a consortium of vitamin C experts including Dr Marcela Vizcaychipi from the Faculty of Medicine at London’s Imperial College, Associate Professor Anitra Carr who heads the Nutrition in Medicine group at the University of Otago , and Dr Paul Marik, chief of the Division of Pulmonary & Critical Care Medicine, Eastern Virginia Medical School.
Dr Vizcaychipi, who heads research in intensive care medicine at the UK’s Chelsea & Westminster Hospital, has been giving Covid and non-Covid patients in their intensive care Units up to 6 grams (6,000 mg) of vitamin C intravenously. The dosage is dependent on the severity of disease and the amount needed to correct deficiency, as indicated by vitamin C urine test sticks.
“Vitamin C is certainly one of multiple factors that contributes to better outcomes and speed of recovery. It should be standard practice. We have not had any safety issues at all.” says Dr Vizcaychipi.
In the US, a group of medical doctors, members of the Frontline Covid Critical Care Alliance have more than halved mortality in their ICUs using a protocol of steroids (methylprednisolone), plus vitamin C (ascorbic acid), plus vitamins B1 (thiamine), D and anticoagulants (heparin) – a strategy known as MATH+. This protocol was pioneered by Drs Paul Marik, Pierre Kory, and Joseph Varon, a critical care expert recognized by the United Nations for his life-saving work.
What the review of 12 clinical trials shows is that “intravenous vitamin C may improve oxygenation parameters, reduce inflammatory markers, decrease days in hospital and reduce mortality, particularly in the more severely ill patients.”
What is remarkable about vitamin C is that it is an antioxidant, an anti-viral, and also anti-inflammatory. It’s an impressive three-in-one defender. Not one adverse event has been reported in any published vitamin C clinical trials in COVID-19 patients.
The review also shows that high doses of oral vitamin C taken upon infection may keep people out of the hospital because it increases their rate of recovery.
According to Carr “Oral doses of 8 grams per day have been shown to increase the rate of recovery from symptomatic infection by 70%. For more critically ill patients, trials using doses of 6-24g a day intravenously have shown positive benefits in terms of increased survival, and reduced hospital stay, improved oxygenation or reduced inflammation.”
It takes twenty oranges to provide a total of only one gram of vitamin C, so these doses require supplementation. The review includes several studies showing that “patients with severe respiratory infections have depleted vitamin C status, with the prevalence of deficiency increasing with the severity of the condition.”
In one study, vitamin C levels predicted who would or wouldn’t survive. Plasma levels of vitamin C were reported to be very low in 70-80% of Covid patients. What is clear is that several grams, not just a glass of orange juice, are needed to correct severe vitamin C deficiency.
Antioxidants from mitochondria protect cells from dying
Coenzyme Q distribution within the cell is regulated by mitochondria
Max Planck Institute for Biology of Ageing, January 30, 2023
Antioxidants are often advertised as a cure-all in nutrition and offered as dietary supplements. However, our body also produces such radical scavengers itself, one of which is coenzyme Q. Now researchers from the Max Planck Institute for Biology of Ageing in Cologne, Germany, have discovered how the substance, which is produced in our mitochondria, reaches the cell surface and protects our cells from dying.
A deficiency of coenzyme Q leads to serious diseases such as Leigh syndrome – a hereditary disease in which certain brain regions become affected and, among other things, muscle weakness can occur. A deficiency of coenzyme Q is also one of the first signs of ageing and can occur as early as the early 20s. But why can’t we simply take this substance in with our food?
“Coenzyme Q is a highly hydrophobic molecule that our bodies absorb very little from food,” explains Soni Deshwal, scientist at the Max Planck Institute for Biology of Aging and lead author of the study. But it is also a problem in our cells that coenzyme Q is not water soluble. The antioxidant is formed in mitochondria and must pass through the watery cell interior called cytoplasm to the surface of the cells in order to neutralize oxidized lipid species. “With our research, we have now been able to identify the proteins involved in coenzyme Q transport from the mitochondria to the cell surface”, explains Deshwal. The researchers found that an enzyme called STARD7 helps transport the coenzyme. This protein is not only localized in the mitochondria, but also inside the cytoplasm.
“The mitochondria actively transport coenzyme Q to the cell surface to protect cells from cell death. It is as if the mitochondria deliver band-aids to the surface to protect the cell”, says Deshwal. “This again shows that mitochondria are not only important as an energy supplier for our cells, but also play crucial regulatory roles.” In the long term, the researchers hope that a precise understanding of this transport process will enable Coenzyme Q to be delivered into the cells of affected patients and thus provide a new therapeutic approach for diseases such as Leigh syndrome.
New Study Links Strength and Biological Age
University of Michigan, January 31, 2023
According to a new study from the University of Michigan, the strength of your grip may be an accurate predictor to measure longevity.
The study, published in the Journal of Cachexia, Sarcopenia and Muscle, followed more than 1,200 middle-aged and older adults over an 8-10 year period, and focused on the relationship between grip strength and a specific model of aging—DNA methylation patterns—using three different “age acceleration clocks.” These clocks were used to calculate biological age, the measurement of age based on a variety of biomarkers, and the rate of aging compared to chronological age, which is the amount of time that has passed from a person’s birth.
The results revealed an association between weaker grip strength and biological age acceleration in both older men and women. Or, to put it more simply, those with a strong grip are more likely to have a younger biological age compared to those whose hand grip strength is considered weak.
According to the lead author of the study, Mark Peterson, Ph.D., M.S., this observation shows the potential for primary care providers to use grip strength as an indicator of risk factors for various health conditions. “We’ve known that muscular strength is a predictor of longevity, and that weakness is a powerful indicator of disease and mortality,” Dr. Peterson explained, “but, for the first time, we have found strong evidence of a biological link between muscle weakness and actual acceleration in biological age.”
Vitamin B3, fiber ‘protects against colon cancer and inflammation’
Georgia Regents University, January 20, 2023
Previous research has suggested that a diet rich in fiber may reduce the risk of colon inflammation and cancer. But new research suggests that niacin, also known as vitamin B3, may also help protect against these conditions.
The research team, including co-author Dr. Vadivel Ganapathy of the Medical College of Georgia at Georgia Regents University, says their findings help explain why a diet high in fiber can reduce the risk of colon-related health conditions and suggests that niacin – supplements already used to regulate cholesterol – can keep the colon healthy for people who have low-fiber diets.
They discovered that mice who were missing a receptor called Gpr109a were more likely to develop inflammation and cancer of the colon.
But on giving niacin to mice who had no healthy colonic bacteria – because it had been destroyed by antibiotics – the researchers found the vitamin pushed immune cells into an anti-inflammatory mode.
Immune cell receptor activated by fiber digestion
The digestion of fiber leads to the production of butyrate – a short-chain fatty acid. Previous research by Dr. Singh revealed that butyrate activates the Gpr109a receptor. But he says that this only seems to happen in the colon and that a high-fiber diet significantly increases butyrate levels in this area.
Butyrate triggers the Gpr109a receptor in immune cells – macrophages and dendritic cells – in the colon.
Dr. Singh notes that this process is crucial when in comes to healing intestinal inflammation that is found in medical conditions such as Crohn’s disease and ulcerative colitis.
Niacin has colon-protecting properties
Dr. Singh notes that their findings suggest high doses of niacin may have a similar effect, which is good news for individuals who have a diet low in fiber.
He adds:
“We think mega-doses of niacin may be useful in the treatment and/or prevention of ulcerative colitis, Crohn’s disease, and colorectal cancer as well as familial adenomatous polyposis, or FAP, a genetic condition that causes polyps to develop throughout the gastrointestinal tract.”
New study finds depression, poor mental health linked to higher heart disease risks among young adults
Johns Hopkins University School of Medicine, January 30, 2023
Young adults who feel down or depressed are more likely to develop cardiovascular disease (CVD) and have poor heart health, according to a new study led by Johns Hopkins Medicine researchers who analyzed data from more than a half million people between the ages of 18 and 49. The findings add to a growing body of evidence connecting CVD with depression among young and middle-aged adults, and suggest the relationship between the two could begin in early adulthood.
The study, published in the Journal of the American Heart Association, also found that young adults who self-reported feeling depressed or having poor mental health days had higher rates of heart attacks, strokes and risk factors for heart disease compared with their peers without mental health issues.
Sharma and her colleagues looked at data from 593,616 adults who participated in the Behavioral Risk Factor Surveillance System, a self-reported, nationally representative survey conducted between 2017 and 2020. The survey included questions about whether they have ever been told they have a depressive disorder, how many days they experienced poor mental health in the past month (0 days, 1–13 days or 14–30 days), whether they had experienced a heart attack, stroke or chest pain, and if they had cardiovascular disease risk factors.
One in five adults self-reported having depression or frequently feeling low, with the study noting that there could have been higher rates during the last year of the study, which was the first year of the COVID-19 pandemic. According to the U.S. Centers for Disease Control and Prevention, the percentage of U.S. adults who experienced depression or anxiety jumped from 36.4% to 41.5% during the first year of the pandemic, with the highest spike among people ages 18 to 29.
The study revealed that, overall, those who self-reported several days of feeling down had a stronger link to cardiovascular disease and poor heart health. Compared with people who reported no poor mental health days in the past 30 days, participants who reported up to 13 poor mental health days had 1.5 times higher odds of CVD, while those with 14 or more days of poor mental health had double the odds. Associations between poor mental health and CVD did not differ significantly by gender or urban/rural status.
“Our study suggests that we need to prioritize mental health among young adults and perhaps increase screening and monitoring for heart disease in people with mental health conditions and vice versa to improve overall heart health.”
Study links poor sleep in seniors to more severe arteriosclerosis
University of Toronto, January 20, 2023
Poor sleep quality in older people is associated with more severe arteriosclerosis in the brain as well as a greater burden of oxygen-starved tissue (infarcts) in the brain, both of which can contribute to the risk of stroke and cognitive impairment, according to the newest findings reported in the American Heart Association’s journal Stroke.
The relationship between cardiovascular disease and so-called “fragmented” sleep has been studied in the past, but this is the first study to look specifically for an association between sleep fragmentation and detailed microscopic measures of blood vessel damage and infarcts in autopsied brain tissue from the same individuals.
Fragmented sleep occurs when sleep is interrupted by repeated awakenings or arousals. In this study, sleep was disrupted on average almost seven times per hour.
Researchers examined autopsied brains of 315 people (average age 90, 70 percent women) who had undergone at least one full week of around-the clock monitoring for rest or activity, from which sleep quality and circadian rhythms were quantified. In all, 29 percent of the patients had suffered a stroke, while 61 percent had signs of moderate to severe damage to their blood vessels in the brain.
Researchers found that greater sleep fragmentation was associated with 27 percent higher odds of having severe arteriosclerosis. Moreover, for each additional two arousals during one hour of sleep, researchers reported a 30 percent increase in the odds that subjects had visible signs of oxygen deprivation in their brain.
These findings were independent of other cardiovascular risk factors (body mass, smoking history, diabetes and hypertension, among others) or other medical conditions (Alzheimer’s disease, pain, depression, heart failure, etc.) researchers said.
Dr. Andrew added there are several ways to view the findings: Sleep fragmentation might impair the circulation of blood to the brain. Or poor circulation of blood to the brain might cause sleep fragmentation. Or both might be caused by another underlying risk factor, he said.